DHX36 Antibody Blocking Peptide(bs-14319P)-500ug

DHX36 Antibody Blocking Peptid

e(bs-14319P)-500ug
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  • bs-14319P
  • 2025年10月16日
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      500ug

    产品编号bs-14319P
    英文名称DHX36 Antibody Blocking Peptide
    中文名称DHX36蛋白封闭多肽
    英文别名DDX36; DEAH box protein 36; Dhx36; DHX36_HUMAN; EC 3.6.1.-; KIAA1488; MLE like protein 1; MLE-like protein 1; MLEL1; Probable ATP dependent RNA helicase DHX36; Probable ATP-dependent RNA helicase DHX36; RHAU; RNA helicase associated with AU rich element ARE; RNA helicase associated with AU-rich element ARE.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing

    亚细胞定位Nucleus. Cytoplasm. Isoform 1 preferentially localized to the nucleus and isoform 2 localized to the cytoplasm. However, partitioning of cellular localization between the nucleus and cytoplasm is not exclusive, as isoform 1 was also detected in the cytoplasm. Both isoforms were excluded from nucleoli.
    组织特异性Highly expressed in testis.
    相似性Belongs to the DEAD box helicase family. DEAH subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    功能Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

     

     

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