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- 2025年10月16日
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500ug
| 产品编号 | bs-2491P |
| 英文名称 | CD27 Antibody Blocking Peptide |
| 中文名称 | CD27封闭多肽 |
| 英文别名 | CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor immunology > CD markers Cancer > Tumor immunology > Cytokines > TNF Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Adaptive Immunity > T Cells > CD Immunology > Innate Immunity > Cytokines > TNF Superfamily Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage |
| 亚基 | Homodimer. Interacts with SIVA1 and TRAF2. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Found in most T-lymphocytes. |
| 翻译后修饰 | Phosphorylated. O-glycosylated with core 1 or possibly core 8 glycans. |
| 相似性 | Contains 3 TNFR-Cys repeats. |
| 功能 | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
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CD27 Antibody Blocking Peptide(bs-2491P)-500ug
￥880
