DGKG Antibody Blocking Peptide(bs-14297P)-500ug

DGKG Antibody Blocking Peptide

(bs-14297P)-500ug
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  • ¥880
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  • bs-14297P
  • 2025年10月16日
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      500ug

    产品编号bs-14297P
    英文名称DGKG Antibody Blocking Peptide
    中文名称甘油二酯激酶γ/DGK-γ封闭多肽
    英文别名DAG kinase gamma; DAGK3; DGK gamma; DGKG; DGKG_HUMAN; diacylglycerol kinase gamma 90kDa; Diacylglycerol kinase gamma; Diglyceride kinase; Diglyceride kinase gamma.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Kinases/Phosphatases

    Neuroscience > Sensory System > Visual system

    Signal Transduction > Metabolism > Lipid metabolism

    Signal Transduction > Signaling Pathway > Lipid Signaling

    亚细胞定位Cell Membrane and Cytoplasmic.
    功能DGKG (Diacylglycerol kinase gamma ) reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. This enzyme initiates resynthesis of phosphoinositides consumed by phospholipase C during cellular signal transduction. DGK gamma is one of multiple DGK isozymes found in animal cells. It is expressed abundantly in the human retina and to a much lesser extent in the brain. Other tissues contain extremely low levels.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

     

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