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- bs-2617P
- 2025年10月16日
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500ug
| 产品编号 | bs-2617P |
| 英文名称 | S-100A13 Antibody Blocking Peptide |
| 中文名称 | S100A13封闭多肽 |
| 英文别名 | Protein S100 A13; S100 calcium binding protein A13; S10AD_HUMAN; Protein S100-A13; S100 calcium-binding protein A13; S100a13. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Signal Transduction > Growth Factors/Hormones > FGF |
| 亚基 | Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1. |
| 亚细胞定位 | Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions. |
| 组织特异性 | Expressed in heart and skeletal muscle. |
| 相似性 | Belongs to the S-100 family. Contains 1 EF-hand domain. |
| 功能 | Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
【翻译】Development trends for monoclonal antibody cancer therapeutics
has more than tripled since the 1980s, from 4.3 per year in the 1980s to 8.3 per year in the 1990s and 13.3 per year for 2000–2005. One reason for the increased investment in mAbs was the evolution of the discovery technology. The initial method for producing mAbs
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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