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- bs-3115P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-3115P |
| 英文名称 | Phospho-Dab1 (Tyr232) Antibody Blocking Peptide |
| 中文名称 | 磷酸化Disabled 1封闭多肽 |
| 英文别名 | Dab1 (phospho Y232); Dab1 (phospho Tyr232); p-Dab1 (phospho Y232); Dab 1; Disabled homolog 1; Disabled homolog 1 Drosophila; Scm; Scr; Scrambler; Yot; Yotari; Dab, reelin signal transducer, homolog 1 (Drosophila); Dab1; DAB1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neural Signal Transduction Signal Transduction > Protein Trafficking > Vesicle Transport > Adapters |
| 亚基 | Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1. Interacts with LRP1. |
| 翻译后修饰 | Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also phosphorylated on Ser-524 independently of reelin signaling. |
| 相似性 | Contains 1 PID domain. |
| 功能 | Adapter molecule functioning in neural development. May regulate SIAH1 activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
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Phospho-Dab1 (Tyr232) Antibody Blocking Peptide(bs-3115P)-500ug
￥1080
