- ￥880
- Bioss
- bs-1558P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1558P |
| 英文名称 | COL7A1 Antibody Blocking Peptide |
| 中文名称 | 7型胶原封闭多肽 |
| 英文别名 | Collagen Type VII; Alpha 1 type VII collagen; COL7A1; Collagen alpha 1(VII) chain; Collagen type VII alpha 1; Collagen VII alpha 1 polypeptide; CollagenVII; EBD 1; EBD1; EBDCT; EBR 1; EBR1; LC collagen; Long chain collagen. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Collagen |
| 亚基 | Homotrimer. Interacts with MIA3/TANGO1; facilitating its loading into transport carriers and subsequent secretion. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix, basement membrane. |
| 翻译后修饰 | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
| 相似性 | Contains 1 BPTI/Kunitz inhibitor domain.
Contains 9 fibronectin type-III domains. Contains 2 VWFA domains. |
| 功能 | Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. |
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COL7A1 Antibody Blocking Peptide(bs-1558P)-500ug
￥880
