IFT81 Antibody Blocking Peptide(bs-15565P)-500ug

IFT81 Antibody Blocking Peptid

e(bs-15565P)-500ug
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  • ¥880
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  • bs-15565P
  • 2025年10月16日
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      500ug

    产品编号bs-15565P
    英文名称IFT81 Antibody Blocking Peptide
    中文名称细胞纤毛内转运同源蛋白81封闭多肽
    英文别名Carnitine deficiency associated expressed in ventricle 1 isoform 2; Carnitine deficiency-associated protein expressed in ventricle 1; CDV-1; CDV1; CDV1R; Ift81; IFT81_HUMAN; intraflagellar transport 81 homolog (Chlamydomonas); Intraflagellar transport protein 81 homolog.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Organelle Proteins

    组织特异性Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis.
    功能Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity).
    Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IFT81 is a 676 amino acid protein that is present at high levels in testis and is moderately expressed in heart, liver, ovary, pancreas, kidney and skeletal muscle. Existing as three alternatively spliced isoforms, two of which are designated CDV-1 and CDV-1R, IFT81 plays a role in testicular development and spermatogenesis and may also be involved in cardiac hypertrophy caused by carnitine deficiency. The gene encoding IFT81 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

     

     

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