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- 技术资料
- 规格:
500ug
| 产品编号 | bs-2577P |
| 英文名称 | GNLY Antibody Blocking Peptide |
| 中文名称 | 颗粒溶素封闭多肽 |
| 英文别名 | Granulysin; D2S69E; LAG2; 519; LAG 2; Lymphocyte activation gene 2; Lymphokine LAG 2; NKG 5; NKG5; Protein NKG5; T cell activation protein 519; T lymphocyte activation gene 519; TLA519. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells Immunology > Innate Immunity > NK Cells |
| 亚细胞定位 | Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation. |
| 组织特异性 | Expressed in natural killer and T-cells. |
| 翻译后修饰 | A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. |
| 相似性 | Contains 1 saposin B-type domain. |
| 功能 | Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GNLY (granulysin) is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. GNLY has antimicrobial activity against M.tuberculosis and other organisms including Gram-positive and Gram-negative bacteria, fungi, and parasites. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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GNLY Antibody Blocking Peptide(bs-2577P)-500ug
¥880







