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- Bioss
- bs-7922P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7922P |
| 英文名称 | POLDIP3 Antibody Blocking Peptide |
| 中文名称 | DNA聚合酶δ相互作用蛋白3封闭多肽 |
| 英文别名 | 46 kDa DNA polymerase delta interaction protein; DNA polymerase delta interacting protein 3; p46; PDIP3_HUMAN; PDIP46; POLDIP3; Polymerase (DNA-directed), delta interacting protein 3; Polymerase delta interacting protein 46; Polymerase delta-interacting protein 3; RNA-binding protein P46; S6K1 Aly/REF-like target; SKAR. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with POLD2. Interacts with NCBP1 and EIF4A3. Associates with the multiprotein exon junction complex (EJC). Interacts with RPS6KB1 (activated). Interacts with ERH. |
| 亚细胞定位 | Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylated at Ser-383 and Ser-385 by RPS6KB1. |
| 相似性 | Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq, Jul 2008]. |
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POLDIP3 Antibody Blocking Peptide(bs-7922P)-500ug
￥880
