- ￥1080
- Bioss
- bs-3006P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-3006P |
| 英文名称 | phospho-ARFIP2 (S260) Antibody Blocking Peptide |
| 中文名称 | 磷酸化ADP核糖基化因子结合蛋白2封闭多肽 |
| 英文别名 | arfaptin 2 (phospho Ser260); arfaptin 2 (phospho S260); ADP ribosylation factor interacting protein 2; Arfaptin 2; ARFIP2; Partner of RAC1; POR1; ARFP2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Adapters > Cytoplasmic |
| 亚基 | Interacts with RAC1 by binding directly to it. Specifically binds to GTP-bound ARF1 and ARF6, but binds to RAC1.GTP and RAC1.GDP with similar affinities. Directly interacts with ARL1 GTP-bound form; this interaction leads to a > 4-fold increase in the amount of ARL1-bound GTP at steady state level. |
| 相似性 | Contains 1 AH domain. |
| 功能 | Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
phospho-ARFIP2 (S260) Antibody Blocking Peptide(bs-3006P)-500ug
￥1080
