EARS2 Antibody Blocking Peptide(bs-17034P)-500ug

EARS2 Antibody Blocking Peptid

e(bs-17034P)-500ug
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  • bs-17034P
  • 2025年10月16日
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      500ug

    产品编号bs-17034P
    英文名称EARS2 Antibody Blocking Peptide
    中文名称KIAA1970蛋白封闭多肽
    英文别名3230401I01Rik; AL024049; EARS 2; EARS2; GluRS; Glutamate--tRNA ligase; mitochondrial; mKIAA1970; MSE1; Probable glutamyl tRNA synthetase, mitochondrial; Probable glutamyl-tRNA synthetase; RGD1307904; SYEM_HUMAN.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Mito. Translation

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNA synthetase

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial translation

    Signal Transduction > Metabolism > Mitochondrial

    翻译后修饰Mitochondrion matrix.
    相似性Belongs to the class-I aminoacyl-tRNA synthetase family.
    功能Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GluRS (glutamyl-tRNA synthetase 2), also known as EARS2 or MSE1, is a 523 amino acid protein that localizes to the mitochondrial matrix and belongs to the class I aminoacyl-tRNA synthetase family. Participating in protein biosynthesis, GluRS functions to catalyze the ATP-dependent attachment of glutamate to tRNA(Glu), a two-step reaction that involves the ATP-dependent activation of glutamate to form Glu-AMP and the subsequent transfer of the glutamate residue to tRNA(Glu).

     

     

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