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500ug
| 产品编号 | bs-17034P |
| 英文名称 | EARS2 Antibody Blocking Peptide |
| 中文名称 | KIAA1970蛋白封闭多肽 |
| 英文别名 | 3230401I01Rik; AL024049; EARS 2; EARS2; GluRS; Glutamate--tRNA ligase; mitochondrial; mKIAA1970; MSE1; Probable glutamyl tRNA synthetase, mitochondrial; Probable glutamyl-tRNA synthetase; RGD1307904; SYEM_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Mito. Translation Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNA synthetase Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial translation Signal Transduction > Metabolism > Mitochondrial |
| 翻译后修饰 | Mitochondrion matrix. |
| 相似性 | Belongs to the class-I aminoacyl-tRNA synthetase family. |
| 功能 | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GluRS (glutamyl-tRNA synthetase 2), also known as EARS2 or MSE1, is a 523 amino acid protein that localizes to the mitochondrial matrix and belongs to the class I aminoacyl-tRNA synthetase family. Participating in protein biosynthesis, GluRS functions to catalyze the ATP-dependent attachment of glutamate to tRNA(Glu), a two-step reaction that involves the ATP-dependent activation of glutamate to form Glu-AMP and the subsequent transfer of the glutamate residue to tRNA(Glu). |
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EARS2 Antibody Blocking Peptide(bs-17034P)-500ug
¥880







