- ￥880
- Bioss
- bs-11403P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11403P |
| 英文名称 | GNRHR2 Antibody Blocking Peptide |
| 中文名称 | 促性腺素释放激素受体2封闭多肽 |
| 英文别名 | GnRH IIR; Putative gonadotropin-releasing hormone II receptor; gonadotropin-releasing hormone (type 2) receptor 2; GnRH-II-R; Type II GnRH receptor; GNRR2_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 翻译后修饰 | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms. |
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GNRHR2 Antibody Blocking Peptide(bs-11403P)-500ug
￥880
