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- Bioss
- bs-13001P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-13001P |
| 英文名称 | DHX15 Antibody Blocking Peptide |
| 中文名称 | DHX15蛋白封闭多肽 |
| 英文别名 | ATP dependent RNA helicase #46; DBP1; DDX15; DEADH box 15; DEAH (Asp Glu Ala His) box polypeptide 15; DEAH box polypeptide 15; DEAH box protein 15; HRH2; PRP43; PrPp43p; RNA; DHX15_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Epigenetics and Nuclear Signaling > Transcription > Co-factors |
| 亚基 | Interacts with SSB/La. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. |
| 亚细胞定位 | Nucleus. Nucleus, nucleolus. |
| 组织特异性 | Ubiquitous. |
| 相似性 | Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| 功能 | The protein encoded by DHX15 is a putative pre mRNA splicing factor ATP dependent RNA helicase. It is thought to be involved in the disassembly of spliceosomes after the release of mature mRNA, and has been implicated in pre mRNA splicing. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX15 (DEAH-box protein 15), also known as DHX15, DBP1 or HRH2, is a nuclear ATP-dependent RNA helicase that is involved in pre-mRNA splicing and is a member of the DEAH-box subfamily of DEAD-box proteins. Expressed throughout the body, DDX15 is a pre-mRNA processing factor that plays a role in spliceosome disassembly after the release of mature mRNA. When localized to the nucleoli, DDX15 is thought to interact with the La/SSB autoantigen, an RNA chaperone that functions in various intracellular processes. DDX15 is 795 amino acids in length and is the human ortholog of the S. cerevisiae protein Prp43. helicase 2. |
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DHX15 Antibody Blocking Peptide(bs-13001P)-500ug
￥880
