- ￥880
- Bioss
- bs-11395P
- 2025年10月16日
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500ug
| 产品编号 | bs-11395P |
| 英文名称 | VAMP8 Antibody Blocking Peptide |
| 中文名称 | 囊泡相关膜蛋白8封闭多肽 |
| 英文别名 | EDB; EnDOBrevin; VAMP 5; VAMP-5; VAMP 8; VAMP-8; VAMP5; VAMP8; VAMP8_HUMAN; Vesicle associated membrane protein 8; Vesicle-associated membrane protein 8. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurotransmission > Secretory Vesicles > SNAPs & SNAREs |
| 亚基 | Found in a number of SNARE complexes with NAPA, SNAP23, SNAP25, STX1A, STX4, STX7, STX8 and VTI1B (By similarity). Interacts with STX8 (By similarity). |
| 亚细胞定位 | Membrane; Single-pass type IV membrane protein. |
| 组织特异性 | Platelets. |
| 相似性 | Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. |
| 功能 | Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. EnDOBrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, enDOBrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. EnDOBrevin interacts specifically with the SNAPs, most likely through an enDOBrevin-containing SNARE complex. |
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VAMP8 Antibody Blocking Peptide(bs-11395P)-500ug
￥880
