CACNB2 Antibody Blocking Peptide(bs-2996P)-500ug

CACNB2 Antibody Blocking Pepti

de(bs-2996P)-500ug
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  • ¥880
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  • bs-2996P
  • 2025年10月16日
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      500ug

    产品编号bs-2996P
    英文名称CACNB2 Antibody Blocking Peptide
    中文名称L-型电压依赖型钙通道β封闭多肽
    英文别名Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Beta; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; calcium channel beta 2c subunit; calcium channel L-type beta 2 subunit; CACB2_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Calcium Signaling > Calcium Channels > L-type

    亚基The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with RRAD. Interaction with RRAD regulates the trafficking of CACNA1C to the cell membrane.
    亚细胞定位Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
    相似性Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
    功能The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]

     

     

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