KIAA1191 Antibody Blocking Peptide(bs-16994P)-500ug

KIAA1191 Antibody Blocking Pep

tide(bs-16994P)-500ug
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  • ¥880
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  • bs-16994P
  • 2025年10月16日
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      500ug

    产品编号bs-16994P
    英文名称KIAA1191 Antibody Blocking Peptide
    中文名称KIAA1191蛋白封闭多肽
    英文别名IR2155535; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; P33MX_HUMAN; Transmembrane protein 2 like; Putative monooxygenase p33MONOX; Brain-derived rescue factor p60MONOX; Flavin monooxygenase motif-containing protein of 33 kDa.
    纯化方法HPLC
    亚基Interacts with COBRA1, NOL12 and PRNP.
    亚细胞定位Cytoplasm.
    组织特异性Down-regulated in the occipital lobe of an early stage Alzheimer disease patients.
    相似性Belongs to the UPF0498 family.
    功能Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料KIAA1191 is a 305 amino acid protein that belongs to the UPF0498 family and exists as three alternatively spliced isoforms. The gene that encodes KIAA1191 consists of approximately 15,908 bases and maps to human chromosome 5q35.2. With 181 million base pairs, Chromosome 5 comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

     

     

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