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- 技术资料
- 规格:
500ug
| 产品编号 | bs-12634P |
| 英文名称 | SMCR7L Antibody Blocking Peptide |
| 中文名称 | SMCR7L蛋白封闭多肽 |
| 英文别名 | dJ1104E15.3; HSU79252; Hypothetical protein LOC54471; MID51; MIEF1; mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kDa; mitochondrial dynamics protein MID51; mitochondrial dynamics protein of 51 kDa; mitochondrial elongation factor 1; SMC7L_HUMAN; SMCR7-like protein; Smcr7l; Smith Magenis syndrome chromosome region candidate gene 7 protein like; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; Smith-Magenis syndrome chromosome region, candidate 7-like. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expression is relatively high in heart, skeletal muscle, pancreas and kidney. |
| 相似性 | Belongs to the SMCR7 family. |
| 功能 | Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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SMCR7L Antibody Blocking Peptide(bs-12634P)-500ug
¥880







