CEP131 Antibody Blocking Peptide(bs-12977P)-500ug

CEP131 Antibody Blocking Pepti

de(bs-12977P)-500ug
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  • ¥880
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  • bs-12977P
  • 2025年10月16日
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      500ug

    产品编号bs-12977P
    英文名称CEP131 Antibody Blocking Peptide
    中文名称中心体蛋白AZI1封闭多肽
    英文别名5 azacytidine induced 1; 5-azacytidine induced 1; 5-azacytidine-induced protein 1; AZ1; Azi; Azi1; AZI1_HUMAN; Centrosomal protein 131 kDa; Centrosomal protein of 131 kDa; Centrosomal protein of 131 kDa; Cep131; Cep131; KIAA1118; OTTMUSP00000004498; Pre-acrosome localization protein 1; RP23 37J21.1.
    纯化方法HPLC
    研究领域

    Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome

    亚细胞定位Cytoplasm > cytoskeleton > centrosome.
    翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    相似性Contains 1 IQ domain.
    功能May play a role in spermatogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料AZI1 is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on treatment with 5-azacytidine, which is known to lead to the demethylation of genomic DNA. The AZI1 gene is conserved in dog, cow, mouse, rat, chicken, and zebrafish, and exists as two alternatively spliced isoforms. AZI1 contains one IQ domain, and the gene that encodes it maps to human chromosome 17q25.3. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

     

     

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