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500ug
| 产品编号 | bs-12977P |
| 英文名称 | CEP131 Antibody Blocking Peptide |
| 中文名称 | 中心体蛋白AZI1封闭多肽 |
| 英文别名 | 5 azacytidine induced 1; 5-azacytidine induced 1; 5-azacytidine-induced protein 1; AZ1; Azi; Azi1; AZI1_HUMAN; Centrosomal protein 131 kDa; Centrosomal protein of 131 kDa; Centrosomal protein of 131 kDa; Cep131; Cep131; KIAA1118; OTTMUSP00000004498; Pre-acrosome localization protein 1; RP23 37J21.1. |
| 纯化方法 | HPLC |
| 研究领域 | Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome |
| 亚细胞定位 | Cytoplasm > cytoskeleton > centrosome. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Contains 1 IQ domain. |
| 功能 | May play a role in spermatogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | AZI1 is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on treatment with 5-azacytidine, which is known to lead to the demethylation of genomic DNA. The AZI1 gene is conserved in dog, cow, mouse, rat, chicken, and zebrafish, and exists as two alternatively spliced isoforms. AZI1 contains one IQ domain, and the gene that encodes it maps to human chromosome 17q25.3. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
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CEP131 Antibody Blocking Peptide(bs-12977P)-500ug
¥880







