- ￥880
- Bioss
- bs-16955P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16955P |
| 英文名称 | KHDRBS2 Antibody Blocking Peptide |
| 中文名称 | KHDRBS2蛋白封闭多肽 |
| 英文别名 | 6330586C16Rik; bA535F17.1; FLJ38664; hSLM 1; KH domain containing, RNA binding, signal transduction associated 2; MGC26664; Sam68 like mammalian protein 1; SLM 1; SLM1. |
| 纯化方法 | HPLC |
| 亚基 | Self-associates to form homooligomers. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen,thymus, ovary and colon. |
| 相似性 | Belongs to the KHDRBS family. Contains 1 KH domain. |
| 功能 | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KHDRBS2 (KH domain containing, RNA binding, signal transduction associated 2), is an RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer and may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. |
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KHDRBS2 Antibody Blocking Peptide(bs-16955P)-500ug
￥880
