phospho-Cdc37 (Ser13) Antibody Blocking Peptide(bs-2815P)-500ug

phospho-Cdc37 (Ser13) Antibody

Blocking Peptide(bs-2815P)-500ug
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  • bs-2815P
  • 2025年10月16日
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      500ug

    产品编号bs-2815P
    英文名称phospho-Cdc37 (Ser13) Antibody Blocking Peptide
    中文名称磷酸化细胞分化周期蛋白37封闭多肽
    英文别名Cdc37 (phospho S13); Cdc37 (phospho Ser13); p-Cdc37 (phospho S13); CDC 37; Cdc37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; CDC37 cell division cycle 37, S cerevisiae, homolog of; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; cell division cycle 37; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc37; S cerevisiae hypothetical protein CDC37.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Kinases/Phosphatases > Cdk Regulators

    Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdk Regulators

    亚基Forms a complex with Hsp90/HSP90AB1 and CDK6. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.
    亚细胞定位Cytoplasm.
    翻译后修饰Constitutively sumoylated by UBE2I.
    相似性Belongs to the CDC37 family.
    功能Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]

     

     

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