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- Bioss
- bs-21368P
- 2025年10月16日
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500ug
| 产品编号 | bs-21368P |
| 英文名称 | SCNN1B Antibody Blocking Peptide |
| 中文名称 | 上皮钠通道β封闭多肽 |
| 英文别名 | Amiloride sensitive sodium channel subunit beta; Beta NaCH; ENaC beta; ENaCB; Epithelial Na(+) channel subunit beta; Epithelial Na+ channel beta subunit; Epithelial Na+ channel subunit beta; Epithelial sodium channel beta 2 subunit; Epithelial sodium channel beta 3 subunit; Nonvoltage gated sodium channel 1 beta subunit; SCNNB_HUMAN; Nonvoltage gated sodium channel 1 subunit beta; SCNEB; SCNN 1B; Sodium channel nonvoltage gated 1 beta (Liddle syndrome); Sodium channel nonvoltage gated 1 beta. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Neuroscience > Neurotransmission > Receptors / Channels > Sodium Channels Neuroscience > Sensory System > Taste system Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚基 | Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. Interacts with the full length immature form of PCSK9 (pro-PCSK9). |
| 亚细胞定位 | Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells. |
| 翻译后修饰 | Phosphorylated on serine and threonine residues (By similarity). |
| 相似性 | Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily. |
| 功能 | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini. |
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SCNN1B Antibody Blocking Peptide(bs-21368P)-500ug
￥880
