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GABARAPL3 Antibody Blocking Pe

ptide(bs-16204P)-500ug
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  • ¥880
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  • bs-16204P
  • 2025年10月16日
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      500ug

    产品编号bs-16204P
    英文名称GABARAPL3 Antibody Blocking Peptide
    中文名称γ氨基丁酸受体相关蛋白样3封闭多肽
    英文别名ATG8D; GABA(A) receptor associated protein like 3; GABA(A) receptors associated protein like 3 pseudogene; GABARAPL3; Gamma-aminobutyric acid receptor associated protein-like 3; GBRL3_HUMAN.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Organelle Proteins

    亚基Interacts with GABRG2 and beta-tubulin (By similarity).
    亚细胞定位Cytoplasmic; cytoskeleton (Probable). Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor (Probable).
    组织特异性Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine.
    翻译后修饰The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL3-II. ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes (By similarity).
    相似性Belongs to the ATG8 family.
    功能Ubiquitin-like modifier involved in autophagosome formation. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

     

     

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