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500ug
| 产品编号 | bs-16204P |
| 英文名称 | GABARAPL3 Antibody Blocking Peptide |
| 中文名称 | γ氨基丁酸受体相关蛋白样3封闭多肽 |
| 英文别名 | ATG8D; GABA(A) receptor associated protein like 3; GABA(A) receptors associated protein like 3 pseudogene; GABARAPL3; Gamma-aminobutyric acid receptor associated protein-like 3; GBRL3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚基 | Interacts with GABRG2 and beta-tubulin (By similarity). |
| 亚细胞定位 | Cytoplasmic; cytoskeleton (Probable). Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor (Probable). |
| 组织特异性 | Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. |
| 翻译后修饰 | The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL3-II. ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes (By similarity). |
| 相似性 | Belongs to the ATG8 family. |
| 功能 | Ubiquitin-like modifier involved in autophagosome formation. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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