CSH2 Antibody Blocking Peptide(bs-12940P)-500ug

CSH2 Antibody Blocking Peptide

(bs-12940P)-500ug
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  • ¥880
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  • bs-12940P
  • 2025年10月16日
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      500ug

    产品编号bs-12940P
    英文名称CSH2 Antibody Blocking Peptide
    中文名称胎盘催乳素1/2封闭多肽
    英文别名Choriomammotropin; Chorionic somatomammotropin B; Chorionic somatomammotropin hormone 2; Chorionic somatomammotropin hormone; CS 2; CS2; CSB; CSH_HUMAN; CSH1; CSH2; hCS B; HCSB; Lactogen; mPL II; mplII; Pl 2; PL; Pl2; Placental lactogen; Placental lactogen II; Prl3b1; Prolactin 3B1; prolactin family 3, subfamily b, member 1; Placental lactogen I; Placental lactogen II; rPLII.
    纯化方法HPLC
    研究领域

    Developmental Biology > Reproduction > Hormones

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚细胞定位Secreted.
    组织特异性Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
    相似性Belongs to the somatotropin/prolactin family.
    功能Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Placental lactogens, also referred to as chorionic somatomammotropin hormones, are protein hormones. They are produced in the mammalian placenta and are similar in structure and function to growth hormones. Together, placental lactogens and growth factors play an essential role to assure successful lactation after pregnancy. Placental lactogens also modify the metabolic state of the mother during pregnancy to supply energy to the fetus. Placental lactogen I is a member of the somatotropin/prolactin family of hormones. The proteins in this family are crucial in mammalian growth control. Placental lactogen I is expressed primarily during mid-pregnancy, and it has been reported that DNA methylation regulates its tissue expression in rats. Placental lactogen II is expressed later in pregnancy and, in mice, its secretion is regulated by the inhibitory control of GH, the concentration of which increases rapidly at the beginning of the last half of pregnancy.

     

     

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