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- bs-14182P
- 2025年10月16日
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500ug
| 产品编号 | bs-14182P |
| 英文名称 | CYP3A5 Antibody Blocking Peptide |
| 中文名称 | 细胞色素P450 3A5封闭多肽 |
| 英文别名 | Aryl hydrocarbon hydroxylase; CP 35; CP35; CP3A5_HUMAN; CYP3A5; CYPIIIA5; Cytochrome P 450; Cytochrome P450 3A5; Cytochrome P450; Cytochrome P450 family 3 subfamily A polypeptide 5; Cytochrome P450 HLp2; Cytochrome P450 subfamily IIIA (niphedipine oxidase) polypeptide 5; Cytochrome P450 subfamily IIIA polypeptide 5; Cytochrome P450-PCN3; DKFZp686L16231; Flavoprotein linked monooxygenase; FLJ31317; HLp 2; HLp2; Microsomal monooxygenase; Niphedipine oxidase; P450 PCN3; P450PCN3; PCN 3; PCN3; Xenobiotic monooxygenase. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Endoplasmic reticulum membrane. Microsome membrane. |
| 相似性 | Belongs to the cytochrome P450 family. |
| 功能 | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010] |
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CYP3A5 Antibody Blocking Peptide(bs-14182P)-500ug
￥880
