BMP2 Antibody Blocking Peptide(bs-10696P)-500ug

BMP2 Antibody Blocking Peptide

(bs-10696P)-500ug
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  • ¥880
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  • bs-10696P
  • 2025年10月16日
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      500ug

    产品编号bs-10696P
    英文名称BMP2 Antibody Blocking Peptide
    中文名称骨形态发生蛋白2封闭多肽
    英文别名Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN.
    纯化方法HPLC
    研究领域

    Cancer > Growth factors > TGF

    Cardiovascular > Angiogenesis > Growth Factors > TGF

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    Signal Transduction > Growth Factors/Hormones > TGF

    Stem Cells > Neural Stem Cells > Extracellular

    Stem Cells > Signaling Pathways > TGF beta > Secreted

    亚基Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN.
    亚细胞定位Secreted.
    组织特异性Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
    相似性Belongs to the TGF-beta family.
    功能Induces cartilage and bone formation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

     

     

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