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- bs-14177P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-14177P |
| 英文名称 | Cyp2b1 Antibody Blocking Peptide |
| 中文名称 | 细胞色素P450 2B1封闭多肽 |
| 英文别名 | Cyp2b 1; Cyp2b 2; Cyp2b1; Cyp2b2; Cypbe; Cytochrome P450 2B1 + 2B2; Cype; CYPIIB1; CYPIIB2; Cytochrome P 450b; Cytochrome P 450b type e; Cytochrome P 450e M; Cytochrome P450 2B1; Cytochrome P450 2B2; Cytochrome P450 family 2 subfamily b polypeptide 1; Cytochrome P450 family 2 subfamily b polypeptide 2; Cytochrome P450 subfamily IIB Phenobarbital inducible b e; ec 1.14.14.1; P450 PB4; P450-B; P450-LM2; P450-PB1 and P450-PB2; P450b; P450E; CP2B1_RAT. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Drug metabolism Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Membrane bound, endoplasmic reticulum |
| 翻译后修饰 | Phosphorylation is accompanied by a decrease in enzyme activity. |
| 相似性 | Belongs to the cytochrome P450 family. |
| 功能 | The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | phenobarbitol-inducible member of the p450 xenobiotic-inducible superfamily involved in hydroxylation of decanoic and other fatty acids [RGD, Feb 2006] |
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