SOHLH2 Antibody Blocking Peptide(bs-12279P)-500ug

SOHLH2 Antibody Blocking Pepti

de(bs-12279P)-500ug
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  • bs-12279P
  • 2025年10月16日
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      500ug

    产品编号bs-12279P
    英文名称SOHLH2 Antibody Blocking Peptide
    中文名称精子卵子结合生成碱性螺旋蛋白2封闭多肽
    英文别名FLJ20449; FLJ57222; Solh2; Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; TEB1; SOLH2_HUMAN.
    纯化方法HPLC
    研究领域

    Developmental Biology > Reproduction > Germ cell markers

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH

    Stem Cells > Germline Stem Cells > Embryonic Germ Cells

    亚细胞定位Nuclear
    相似性Contains 1 bHLH (basic helix-loop-helix) domain.
    功能Sohlh2, spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2, is a basic loop helix transcription factor. Sohlh2 is normally expressed in pre-meiotic germ cells and testis and involved in spermatogenesis and oogenesis. Male Sohlh2 deficient mice are infertile due to a block in spermatogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SOHLH2 is a 425 amino acid nuclear protein that contains one basic helix-loop-helix (bHLH) domain through which it may function as a transcription factor during oogenesis and spermatogenesis. SOHLH2 exists as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 13q13.3. Chromosome 13 houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

     

     

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