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- Bioss
- bs-2493P
- 2025年10月16日
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500ug
| 产品编号 | bs-2493P |
| 英文名称 | TNFRSF12A Antibody Blocking Peptide |
| 中文名称 | 肿瘤坏死因子配体超家族成员12A封闭多肽 |
| 英文别名 | CD 266; CD266; CD266 antigen; TWEAKR; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12A; TNFRSF12A; TNR12_HUMAN; Tumor necrosis factor receptor superfamily member 12A; TWEAK R; Tweak receptor; Tweak-receptor; TweakR; Type I transmembrane protein Fn 14; Type I transmembrane protein Fn14. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > TNF Cardiovascular > Angiogenesis > Growth Factors Signal Transduction > Growth Factors/Hormones > TNF |
| 亚基 | Associates with TRAF1 and TRAF2, and probably also with TRAF3. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas. |
| 相似性 | Contains 1 TNFR-Cys repeat. |
| 功能 | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.Function : Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. |
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TNFRSF12A Antibody Blocking Peptide(bs-2493P)-500ug
￥880
