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- Bioss
- bs-14174P
- 2025年10月16日
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500ug
| 产品编号 | bs-14174P |
| 英文名称 | Cytochrome P450 1A1 + 1A2 Antibody Blocking Peptide |
| 中文名称 | 细胞色素P450 1A1+1A2封闭多肽 |
| 英文别名 | Aryl hydrocarbon hydroxylase; CP11; CP12; CYP1A1; CYP1A2; CYPIA1; CP1A1_HUMAN; CYPIA2; CP1A2_HUMAN; Cytochrome P450 family 1 subfamily A polypeptide 1; Cytochrome P450 family 1 subfamily A polypeptide 2; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 1; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; P1 450; P3 450; P450 form 4; P450 form 6; P450 P1; P450 P3. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Cellular metabolic process Cancer > Cancer Metabolism > Response to hypoxia Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Endoplasmic reticulum |
| 组织特异性 | Lung, lymphocytes and placenta. |
| 相似性 | Belongs to the cytochrome P450 family. |
| 功能 | Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008] |
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Cytochrome P450 1A1 + 1A2 Antibody Blocking Peptide(bs-14174P)-500ug
￥880
