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- bs-15466P
- 2025年10月16日
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500ug
| 产品编号 | bs-15466P |
| 英文名称 | ERVFRD-1 Antibody Blocking Peptide |
| 中文名称 | ERVFRD-1封闭多肽 |
| 英文别名 | SYCY2_HUMAN; EFRD1_HUMAN; Endogenous retrovirus group FRD member 1; Envelope polyprotein; HERV-FRD; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; TM; SU; ERVFRD-1; ERVFRDE1; UNQ6191/PRO20218; |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > Other viruses |
| 亚基 | The surface (SU) and transmembrane (TM) proteins form a heterodimer. SU and TM are attached by noncovalent interactions or by a labile interchain disulfide bond (By similarity). |
| 亚细胞定位 | Virion. Transmembrane protein: Cell membrane; Single-pass membrane protein (Potential). |
| 组织特异性 | Expressed at higher level in placenta. Expressed at lower level in adrenal, bone marrow, brain, breast, colon, kidney, lung, ovary, peripheral blood lymphocytes, prostate, skin, spleen, testis, thymus, thyroid, trachea. |
| 翻译后修饰 | Specific enzymatic cleavages in vivo yield the mature SU and TM proteins (By similarity). The CXXC motif is highly conserved across a broad range of retroviral envelope proteins. It is thought to participate in the formation of a labile disulfide bond possibly with the CX6CC motif present in the transmembrane protein. Isomerization of the intersubunit disulfide bond to an SU intrachain disulfide bond is thought to occur upon receptor recognition in order to allow membrane fusion (By similarity). |
| 相似性 | Belongs to the gamma type-C retroviral envelope protein family. HERV class-I FRD env subfamily. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. Can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.SU mediates receptor recognition (By similarity).TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity). |
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ERVFRD-1 Antibody Blocking Peptide(bs-15466P)-500ug
￥880
