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- Bioss
- bs-15453P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15453P |
| 英文名称 | N6AMT1 Antibody Blocking Peptide |
| 中文名称 | Hemk甲基转移酶家族2号蛋白封闭多肽 |
| 英文别名 | C21orf127; Chromosome 21 open reading frame 127; EC 2.1.1.-; HemK methyltransferase family member 2; HemK2; M.HsaHemK2P; MGC19995; MTQ2; N-6 adenine-specific DNA methyltransferase 1; N-6 adenine-specific DNA methyltransferase 1 (putative); N6-DNa-Methyltransferase; N6AMT; N6AMT1; OTTHUMP00000096393; OTTHUMP00000096394; PRED28; HEMK2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA methylation > DNMTs |
| 亚基 | Heterodimer with TRMT112. |
| 组织特异性 | Widely expressed, with highest expression in parathyroid and pituitary glands, followed by adrenal gland and kidney, and lowest expression in leukocytes and mammary gland. |
| 相似性 | Belongs to the eukaryotic/archaeal PrmC-related family. |
| 功能 | Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HEMK2 is a 214 amino acid protein that belongs to the methyltransferase superfamily and exists as multiple alternatively spliced isoforms. The gene encoding HEMK2 maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21). |
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N6AMT1 Antibody Blocking Peptide(bs-15453P)-500ug
￥880
