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- Bioss
- bs-21247P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21247P |
| 英文名称 | SLC26A8 Antibody Blocking Peptide |
| 中文名称 | 溶质载体转运蛋白家族26成员8封闭多肽 |
| 英文别名 | SLC26A8; Anion exchange transporter; Anion transporter/exchanger 8; FLJ32714; MGC38861; RP11-482O9.1; Solute carrier family 26 (anion exchanger) member 8; Solute carrier family 26, member 8; SPGF3; TAT1; Testis anion transporter 1. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with RACGAP1. Interacts with CFTR. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. Note: Located at the annulus ring structure within the sperm cell. |
| 组织特异性 | Expression observed exclusively in testis, restricted to the meiotic phase of the germ cell. Abundant expression located in the seminiferous tubules, concentrated on the luminal side of the tubuli harboring the spermatocytes and spermatids. Expressed in spermatozoa. |
| 相似性 | Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. Contains 1 STAS domain. |
| 功能 | Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility. May form a moleculer complex involved in the regulation of chloride and bicarbonate ions fluxes during sperm capacitation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010] |
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SLC26A8 Antibody Blocking Peptide(bs-21247P)-500ug
￥880
