PPIE Antibody Blocking Peptide(bs-14138P)-500ug

PPIE Antibody Blocking Peptide

(bs-14138P)-500ug
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  • bs-14138P
  • 2025年10月16日
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      500ug

    产品编号bs-14138P
    英文名称PPIE Antibody Blocking Peptide
    中文名称亲环蛋白(亲环素)E封闭多肽
    英文别名Ab1-210; Cyclophilin 33; Cyclophilin E; Cyclophilin-33; CYP 33; CYP33; EC 5.2.1.8; Peptidyl prolyl cis trans isomerase E; Peptidyl-prolyl cis-trans isomerase E; Peptidylprolyl isomerase E (cyclophilin E); Peptidylprolyl isomerase E; PPIase E; PPIE; PPIE_HUMAN; Rotamase E.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation

    Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

    亚细胞定位Nucleus.
    组织特异性Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
    相似性Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
    Contains 1 PPIase cyclophilin-type domain.
    Contains 1 RRM (RNA recognition motif) domain.
    功能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Combines RNA-binding and PPIase activities. May be involved in muscle- and brain-specific processes. May be involved in pre-mRNA splicing.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]

     

     

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