TSKU Antibody Blocking Peptide(bs-11607P)-500ug

TSKU Antibody Blocking Peptide

(bs-11607P)-500ug
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  • ¥880
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  • bs-11607P
  • 2025年10月16日
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      500ug

    产品编号bs-11607P
    英文名称TSKU Antibody Blocking Peptide
    中文名称TSK蛋白封闭多肽
    英文别名E2 induced gene 4 protein; E2IG4; Leucine rich repeat containing protein 54; LRRC54; TSK; Tsukushi; TSK_HUMAN; Tsukushin.
    纯化方法HPLC
    亚细胞定位Secreted
    相似性Contains 10 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
    功能It is suggested that Tsukushin is involved in intracellular transport and extracellular secretion. Its structure contains 9 LRR (leucine-rich) repeats.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

     

     

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