SP6 Antibody Blocking Peptide(bs-12704P)-500ug

SP6 Antibody Blocking Peptide(

bs-12704P)-500ug
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  • ¥880
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  • bs-12704P
  • 2025年10月16日
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      500ug

    产品编号bs-12704P
    英文名称SP6 Antibody Blocking Peptide
    中文名称转录因子SP6封闭多肽
    英文别名MGC119665; Epfn; EPIPROFIN; KLF14; Krueppel-like factor 14; MGC119662; MGC119663; MGC119664; Sp6; Sp6 transcription factor; SP6_HUMAN; Transcription factor Sp6.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Krueppel like factor

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    Epigenetics and Nuclear Signaling > Transcription > Krueppel like factor

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    亚细胞定位Nucleus.
    组织特异性Ubiquitous.
    相似性Belongs to the Sp1 C2H2-type zinc-finger protein family.
    Contains 3 C2H2-type zinc fingers.
    功能Promotes cell proliferation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96% sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

     

     

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