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- Bioss
- bs-15444P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-15444P |
| 英文名称 | MYH Antibody Blocking Peptide |
| 中文名称 | 心肌肌球蛋白重链封闭多肽 |
| 英文别名 | MYH6 + MYH7; MYH6 / MYH7; Alpha MHC; ASD3; CMD1S; CMH1; MGC138376; MGC138378; MPD1; MYH 6; MYH 7; MYH6; MYH7; MYHC A; MYHC; MYHC B; MyHC-alpha; MyHC-beta; MYHCA; MYHCB; Myosin heavy chain cardiac muscle alpha isoform; Myosin heavy chain cardiac muscle beta isoform; Myosin heavy polypeptide 7 cardiac muscle beta; MYH6_HUMAN; MYH7_HUMAN; heavy chain cardiac Myosin. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Contractility > Contractile Proteins > Myosins Immunology > Immune System Diseases > Autoimmune Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Myosin |
| 亚基 | Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). |
| 亚细胞定位 | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. |
| 组织特异性 | Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). |
| 相似性 | Contains 1 IQ domain. Contains 1 myosin head-like domain. |
| 功能 | Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis, vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8); three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1); and MHC-∫/slow (MYH7 or MHC-∫), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes hypertrophic cardiomyopathy. |
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MYH Antibody Blocking Peptide(bs-15444P)-500ug
￥880
