SLC25A19 Antibody Blocking Peptide(bs-21222P)-500ug

SLC25A19 Antibody Blocking Pep

tide(bs-21222P)-500ug
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  • bs-21222P
  • 2025年10月16日
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      500ug

    产品编号bs-21222P
    英文名称SLC25A19 Antibody Blocking Peptide
    中文名称溶质载体家族25成员19封闭多肽
    英文别名DNC; MCPHA; Mitochondrial thiamine pyrophosphate carrier; Mitochondrial uncoupling protein 1; MUP1; Solute carrier family 25 (mitochondrial deoxynucleotide carrier) member 19; Solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier) member 19; Solute carrier family 25 member 19; TPC.
    纯化方法HPLC
    研究领域

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Signal Transduction > Metabolism > Mitochondrial

    Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria

    亚细胞定位Mitochondrion inner membrane; Multi-pass membrane protein.
    组织特异性Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung, testis, spleen, and brain.
    相似性Belongs to the mitochondrial carrier (TC 2.A.29) family.
    Contains 3 Solcar repeats.
    功能 Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

     

     

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