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500ug
| 产品编号 | bs-21102P |
| 英文名称 | SEZ6L2 Antibody Blocking Peptide |
| 中文名称 | 癫痫相关蛋白6样蛋白2封闭多肽 |
| 英文别名 | FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog (mouse) like 2; SEZ6L2; Type I transmembrane receptor (seizure related protein). |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer. |
| 翻译后修饰 | O-glycosylated with core 1 or possibly core 8 glycans. |
| 相似性 | Belongs to the SEZ6 family. Contains 3 CUB domains. Contains 5 Sushi (CCP/SCR) domains. |
| 功能 | Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
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SEZ6L2 Antibody Blocking Peptide(bs-21102P)-500ug
¥880







