SEZ6L2 Antibody Blocking Peptide(bs-21102P)-500ug

SEZ6L2 Antibody Blocking Pepti

de(bs-21102P)-500ug
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  • bs-21102P
  • 2025年10月16日
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      500ug

    产品编号bs-21102P
    英文名称SEZ6L2 Antibody Blocking Peptide
    中文名称癫痫相关蛋白6样蛋白2封闭多肽
    英文别名FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog (mouse) like 2; SEZ6L2; Type I transmembrane receptor (seizure related protein).
    纯化方法HPLC
    亚细胞定位Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer.
    翻译后修饰O-glycosylated with core 1 or possibly core 8 glycans.
    相似性Belongs to the SEZ6 family.
    Contains 3 CUB domains.
    Contains 5 Sushi (CCP/SCR) domains.
    功能Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

     

     

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