- ￥880
- Bioss
- bs-11542P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11542P |
| 英文名称 | RCAN3 Antibody Blocking Peptide |
| 中文名称 | 钙调神经磷酸酶调节蛋白3封闭多肽 |
| 英文别名 | Calcipressin-3; Down syndrome candidate region 1 like 2; regulator of calcineurin 3; Down syndrome candidate region 1 like protein 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1 like 2; DSCR1L2; hRCN3; MCIP3; Myocyte enriched calcineurin interacting protein 3; Myocyte-enriched calcineurin-interacting protein 3; RCAN family member 3; RCAN3; RCAN3_HUMAN; RCN3; RCN3; MCIP3; Regulator of calcineurin 3. |
| 纯化方法 | HPLC |
| 组织特异性 | Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues. |
| 相似性 | Belongs to the RCAN family. |
| 功能 | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events. |
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RCAN3 Antibody Blocking Peptide(bs-11542P)-500ug
￥880
