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500ug
| 产品编号 | bs-2468P |
| 英文名称 | CCL13 Antibody Blocking Peptide |
| 中文名称 | 单核细胞趋化蛋白4封闭多肽 |
| 英文别名 | Chemokine (C C motif) ligand 13; CCL13; MCP-4; SCYL1; CK beta 10; CKb10; MGC17134; Monocyte chemoattractant protein 4; Monocyte chemotactic protein 4; NCC 1; NCC1; New CC chemokine 1; SCYA13; SCYL1; Small inducible cytokine A13 precursor; Small inducible cytokine subfamily A (Cys Cys) member 13; CCL13_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Chemokines > Beta Chemokines (CC) Immunology > Innate Immunity > Macrophage / Inflamm. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells. |
| 翻译后修饰 | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
| 相似性 | Belongs to the intercrine beta (chemokine CC) family. |
| 功能 | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq]. |
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CCL13 Antibody Blocking Peptide(bs-2468P)-500ug
¥880







