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- Bioss
- bs-6618P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-6618P |
| 英文名称 | PAPPA Antibody Blocking Peptide |
| 中文名称 | 妊娠相关血浆蛋白A封闭多肽 |
| 英文别名 | ASBABP2; Aspecific BCL2 ARE binding protein 2; Differentially placenta 1 expressed protein; DIPLA1; IGF dependent IGFBP 4 protease; IGF-dependent IGFBP-4 protease; IGFBP 4ase; IGFBP-4ase; IGFBP4ase; Insulin like growth factor dependent IGF binding protein 4 protease; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPA; PAPP A; PAPP-A; PAPP1_HUMAN; PAPPA; PAPPA1; Pappalysin 1 precursor; Pappalysin-1; Pregnancy Associated Plasma Protein A; Pregnancy associated plasma protein A pappalysin 1; Pregnancy-associated plasma protein A. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Serum Proteins Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Homodimer; disulfide-linked. In pregnancy serum, predominantly found as a disulfide-linked 2:2 heterotetramer with the proform of PRG2. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | High levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts. |
| 翻译后修饰 | There appear to be no free sulfhydryl groups. |
| 相似性 | Belongs to the peptidase M43B family. Contains 5 Sushi (CCP/SCR) domains. |
| 功能 | Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. |
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PAPPA Antibody Blocking Peptide(bs-6618P)-500ug
￥800
