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- Bioss
- bs-1097P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-1097P |
| 英文名称 | PAX3 Antibody Blocking Peptide |
| 中文名称 | 配对盒基因3封闭多肽 |
| 英文别名 | CDHS; HUP 2; HUP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box homeotic gene 3; Paired box protein Pax 3; Paired box protein Pax3; paired domain gene 3; paired domain gene HuP2; PAX 3; PAX3/FKHR fusion gene; Waardenburg syndrome 1; WS 1; WS1. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Lineage specification > Ectoderm Developmental Biology > Organogenesis > Nervous system development Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > PAX Stem Cells > Lineage Markers > Ectoderm Stem Cells > Mesenchymal Stem Cells > Myogenesis Stem Cells > Neural Stem Cells > Intracellular Stem Cells > Neural Stem Cells > Neural Crest Stem Cells |
| 亚基 | Can bind to DNA as a homodimer or a heterodimer with PAX7. Interacts with PAXBP1; the interaction links PAX3 to a WDR5-containing histone methyltransferase complex. Interacts with DAXX. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain. Contains 1 paired domain. |
| 功能 | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. |
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PAX3 Antibody Blocking Peptide(bs-1097P)-500ug
￥880
