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- Bioss
- bs-10958P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-10958P |
| 英文名称 | SLC32A1 Antibody Blocking Peptide |
| 中文名称 | 氨基丁酸转运蛋白VGAT封闭多肽 |
| 英文别名 | VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasmic vesicle membrane; Multi-pass membrane protein |
| 组织特异性 | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| 相似性 | Belongs to the amino acid/polyamine transporter 2 family. |
| 功能 | Involved in the uptake of GABA and glycine into the synaptic vesicles. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure. |
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SLC32A1 Antibody Blocking Peptide(bs-10958P)-500ug
￥880
