- ￥880
- Bioss
- bs-14045P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14045P |
| 英文名称 | CRB1 Antibody Blocking Peptide |
| 中文名称 | CRB1蛋白封闭多肽 |
| 英文别名 | CRB1; CRUM1_HUMAN; Protein crumbs homolog 1. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Visual system |
| 亚细胞定位 | Secreted and Apical cell membrane. Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina. |
| 组织特异性 | Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. |
| 翻译后修饰 | Extensively glycosylated. |
| 相似性 | Belongs to the Crumbs protein family. Contains 19 EGF-like domains. Contains 3 laminin G-like domains. |
| 功能 | Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012] |
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CRB1 Antibody Blocking Peptide(bs-14045P)-500ug
￥880
