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- 规格:
500ug
| 产品编号 | bs-11522P |
| 英文名称 | NPY4R Antibody Blocking Peptide |
| 中文名称 | 神经肽Y受体4封闭多肽 |
| 英文别名 | Neuropeptide Y receptor type 4; Neuropeptide Y receptor Y4; NPY 4R; NPY R4; NPY Y4; NPY Y4 receptor; NPY-Y4 receptor; NPY4 R; NPY4-R; NPY4R; NPY4R_HUMAN; NPYR 4; NPYR4; NPYY 4; NPYY4; NPYY4-R; Y4 receptor. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | NPY4R has been reported to be expressed in bladder, brain, colon, endometrium, heart, lung, nasal mucosa, penis, prostate, skeletal muscle, small intestine, stomach, and vessel. ESTs have been isolated from human colon and head/neck libraries. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. |
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NPY4R Antibody Blocking Peptide(bs-11522P)-500ug
¥880





