HGF Antibody Blocking Peptide(bs-1025P)-500ug

HGF Antibody Blocking Peptide(

bs-1025P)-500ug
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  • bs-1025P
  • 2025年10月16日
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      500ug

    产品编号bs-1025P
    英文名称HGF Antibody Blocking Peptide
    中文名称肝细胞生长因子α封闭多肽
    英文别名HGF alpha; HGFA; F TCF; Hepatocyte growth factor; Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor precursor; Hepatopoietin A; HPTA; Lung fibroblast derived mitogen; Scatter factor; SF; hepatocyte growth factor alpha-chain; Hepatocyte growth factor alpha chain; HGF_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚基Dimer of an alpha chain and a beta chain linked by a disulfide bond.
    相似性Belongs to the peptidase S1 family. Plasminogen subfamily.
    Contains 4 kringle domains.
    Contains 1 PAN domain.
    Contains 1 peptidase S1 domain.
    功能HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料HGF is a pleiotropic protein in the plasminogen subfamily of S1 peptidases. HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Human HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF regulates many physiological processes including proliferation, scattering, morphogenesis and survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries.This recombinant human HGF is produced by human cells. (Tag free) Biological activity: The activity was measured by its ability to stimulate the proliferation of the monkey epithelial cell line 4MBr-5.Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

     

     

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