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- Bioss
- bs-11478P
- 2025年10月16日
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500ug
| 产品编号 | bs-11478P |
| 英文名称 | SEMA4F Antibody Blocking Peptide |
| 中文名称 | 跨膜蛋白SEMA4F封闭多肽 |
| 英文别名 | M SEMA; m Sema M; PRO2353; Sema domain immunoglobulin domain (Ig) transmembrane; Sema M; Sema W; SEMAM; Semaphorin M; Semaphorin W; SEMAW; SEM4F_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins Neuroscience > Sensory System > Visual system |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein |
| 相似性 | Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 PSI domain. Contains 1 Sema domain. |
| 功能 | SEMA4F has growth cone collapse activity against retinal ganglion-cell axons. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4F (semaphorin-4F), also known as SEMAM, SEMAW or PRO2353, is a 770 amino acid member of the semaphorin family. Localized to the membrane, SEMA4F is a single-pass type I protein that is involved in growth cone collapse of retinal ganglion-cell axons. SEMA4F is highly expressed in postnatal brain and lung and contains one immunogloblin-like (Ig-like) domain, one PSI domain and one semaphorin domain. Two isoforms exist due to alternative splicing events. |
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SEMA4F Antibody Blocking Peptide(bs-11478P)-500ug
￥880
