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500ug
| 产品编号 | bs-15346P |
| 英文名称 | CARD19 Antibody Blocking Peptide |
| 中文名称 | 9号染色体开放阅读框89封闭多肽 |
| 英文别名 | Bcl10 interacting protein with CARD protein; BinCARD; Chromosome 9 open reading frame 89; BINCA_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Signaling Pathway > Nuclear Signaling > NFkB Pathway |
| 亚基 | Associates with BCL10 by CARD-CARD interaction. |
| 亚细胞定位 | Nucleus. Note=Co-expression with BCL10 induced translocation from nucleus to cytosol. |
| 组织特异性 | Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain. |
| 翻译后修饰 | Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Contains 1 CARD domain. |
| 功能 | Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C9orf89 plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. It may inhibit the phosphorylation of BCL10 in a CARD-dependent manner. There are two isoforms. |
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CARD19 Antibody Blocking Peptide(bs-15346P)-500ug
¥880







