VPS26 Antibody Blocking Peptide(bs-12768P)-500ug

VPS26 Antibody Blocking Peptid

e(bs-12768P)-500ug
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  • bs-12768P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-12768P
    英文名称VPS26 Antibody Blocking Peptide
    中文名称液泡蛋白分选蛋白26封闭多肽
    英文别名FLJ12930; HB 58; HB58; Hbeta 58; Hbeta 58 homolog; Hbeta58; Hbeta58 homolog; hVPS 26; hVPS26; MGC94168; PEP 8A; PEP8A; Vacuolar protein sorting 26 A; Vacuolar protein sorting 26; Vacuolar protein sorting 26 homolog A; Vacuolar protein sorting 26 homolog A S. pombe; Vacuolar protein sorting 26 homolog A yeast; Vacuolar protein sorting 26 yeast; Vacuolar protein sorting 26 yeast homolog; Vacuolar protein sorting 26A; Vacuolar protein sorting associated protein 26A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26; Vesicle protein sorting 26A; VP26A_HUMAN; VPS 26; VPS 26A; VPS26A.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Golgi Proteins

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚细胞定位Cytoplasm. Endosome membrane.
    相似性Belongs to the VPS26 family.
    功能Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

     

     

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