- ￥2080 - 28000
- Bioss
- bs-48001P
- 2025年10月16日
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- 详细信息
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- 规格：
10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥2080.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥6800.0 |
| 规格： | 500ug | 产品价格： | ￥28000.0 |
| 产品编号 | bs-48001P |
| 英文名称 | Recombinant human IL-1b protein (Active, HEK293) |
| 中文名称 | 重组人白细胞介素-1β (活性的, Tag free) |
| 英文别名 | Catabolin; H1; IL-1β; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta; IL1B_HUMAN; Interleukin-1 beta; IL-1 beta; Recombinant human IL-1b protein (Active, HEK293) |
| 中文别名 | IL-1 beta 重组蛋白; 白细胞介素-1β; 重组人白细胞介素-1β; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 实际分子量 | 18-25 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators Immunology > Innate Immunity > Cytokines > Interleukins Metabolism > Types of disease > Obesity Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus |
| 亚基 | Monomer. |
| 亚细胞定位 | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| 相似性 | Belongs to the IL-1 family. |
| 功能 | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. |
The purity of the protein is greater than 95% as determined by non reduced and reduced SDS-PAGE
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Recombinant human IL-1b protein (Active, HEK293)(bs-48001P)-10ug/50ug/500ug
￥2080 - 28000
